Thermo Fisher Scientific TAS2R4 Polyclonal Antibody
TAS2R4 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 합성 펩타이드를 면역원으로 사용하였으며 비결합형 상태로 제공됩니다. 동결건조 형태로 공급되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from a cytoplasmic domain of mouse TAS2R4 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TAS2R4.
Target Information
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless genes encode a 7-transmembrane receptor protein functioning as a bitter taste receptor.
This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. It acts as a gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil, implicated in the perception of bitter compounds in the oral cavity and gastrointestinal tract. Signals through PLCB2 and TRPM5 channels. Expressed in subsets of taste receptor cells of the tongue and palate epithelium, exclusively in gustducin-positive cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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