Thermo Fisher Scientific TAS2R16 Polyclonal Antibody
Thermo Fisher Scientific의 TAS2R16 폴리클로날 항체는 Rat 종에 반응하며, Western blot 및 IHC에 적합합니다. 합성 펩타이드 항원을 기반으로 제작되었으며, 동결건조 형태로 제공됩니다. TAS2R16 단백질 특이성을 가지며 연구용으로 사용됩니다.
- 카탈로그번호
- OST00279W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:2,000
Miscellaneous PubMed (Misc)
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from a cytoplasmic domain of rat TAS2R16 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TAS2R16.
Target Information
This gene encodes a member of a family of candidate taste receptors belonging to the G protein-coupled receptor superfamily. These receptors are expressed by taste receptor cells of the tongue and palate epithelia. Each gene encodes a 7-transmembrane receptor protein functioning as a bitter taste receptor.
The TAS2R16 gene is clustered with other candidate taste receptor genes on chromosome 7 and is genetically linked to loci influencing bitter perception. It acts as a gustducin-coupled receptor involved in bitter compound detection in the oral cavity and gastrointestinal tract, signaling through PLCB2 and TRPM5 channels. Expressed in a subset of gustducin-positive taste receptor cells of the tongue. The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism and confers bitter perception of salicin to non-taster mice.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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