Thermo Fisher Scientific SIRT6 Monoclonal Antibody (OTI1G3), TrueMAB
SIRT6 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 면역세포염색에 적합합니다. 인간 시료에 반응하며, 동결건조 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, DNA 복구 및 노화 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 88–352 of human SIRT6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Sirtuins regulate epigenetic gene silencing.
SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6) is a chromatin-associated nuclear ADP-ribosyltransferase protein and a mouse Sir2 homolog.
It is involved in DNA repair and may play a role in human aging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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