Thermo Fisher Scientific INHA Polyclonal Antibody
Thermo Fisher Scientific의 INHA Polyclonal Antibody는 인간 및 랫트 반응성을 가지며 Western blot, ICC/IF, Flow cytometry에 적합합니다. 합성 펩타이드 항원 기반으로 제작되었으며, 액상 형태로 1 mg/mL 농도입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human Inhibin alpha chain (aa 100–200/366) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913481 |
Product Specific Information
- Positive Control: K562 cell lysate, Hela cell lysate, rat testis tissue lysates, MCF-7, Hela, SiHa
- Subcellular Location: Secreted
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and has tumor-suppressor activity. Serum levels of inhibin reflect granulosa-cell tumor size and can serve as a marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed and undetectable in poorly differentiated tumor cells. Expression varies by tissue type, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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