Thermo Fisher Scientific Phospho-MEF2C (Ser387) Polyclonal Antibody

Applications

• Dot blot (DB): Tested dilution 1:500

Product Specifications

Product Specific Information

This antibody is predicted to react with porcine based on sequence homology.

Target Information

MEF2C is a transcription activator that binds specifically to the MEF2 element present in regulatory regions of many muscle-specific genes. It controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by regulating excitatory synapses and synaptic transmission. Crucial for normal neuronal development and electrical activity in the neocortex. Necessary for proper development of megakaryocytes, platelets, and bone marrow B lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation and normal induction of germinal center B cells. May also play a role in neurogenesis and cortical architecture development. Isoform 3 and 4, lacking the repressor domain, are more active than isoform 1 and 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지: PA5-12814_MEF2C_Q06413-1_Rabbit.svg, PA5-12814_MEF2C_Q06413-1_Rabbit_PDP.jpeg)