Thermo Fisher Scientific Phospho-VPS34 (Ser164) Polyclonal Antibody
Phospho-VPS34 (Ser164) 폴리클로날 항체로 인간 VPS34 단백질의 인산화 형태를 검출. Western blot 및 Dot blot에 적합하며, Protein A 및 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 보관하며 연구용으로 사용.
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- PA512829
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- pk
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Thermo Fisher Scientific Phospho-VPS34 (Ser164) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Dot Blot (DB) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S164 of human PI3KC3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2165121 |
Product Specific Information
This antibody is predicted to react with mouse, porcine, and rat based on sequence homology.
Target Information
PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. It phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes.
PIK3C3 is involved in coupling nutrient signaling to mTOR and plays roles in autophagy and intracellular trafficking. It regulates degradative endocytic trafficking and is required for the abscission step in cytokinesis, likely in the context of PI3KC3-C2. It also participates in the transport of lysosomal enzyme precursors from early to late endosomes.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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