Thermo Fisher Scientific USP35 Polyclonal Antibody
Thermo Fisher Scientific의 USP35 폴리클로날 항체로 인간 USP35 단백질을 인식합니다. IHC(P)에서 1:50–1:200 희석으로 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 장기보관 시 -20°C에서 보관합니다.
- 카탈로그번호
- PA563591
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human USP35. Recombinant protein control fragment (Product #RP-101227). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649344 |
Product Specific Information
- Immunogen sequence:
LYLQEQEKEA RSRAAYISAL PTSPHWGRGF DEDKDEDEGS PGGCNPAGGN GGDFHRLVF - Highest antigen sequence identity to orthologs:
- Mouse: 93%
- Rat: 90%
Target Information
p73 protein is a member of the p53 family of proteins. The tumor-suppressor protein p53 exhibits sequence-specific DNA binding, interacts with various cellular and viral proteins, and induces cell cycle arrest in response to DNA damage. Upon genotoxic stress such as UV irradiation or DNA damage, p53 accumulates in the nucleus through post-translational modifications. Activation of p53 can lead to cell cycle arrest or apoptosis, preventing proliferation of genetically damaged cells. These p53-dependent pathways maintain genomic stability by eliminating damaged cells. High levels of p53 accumulation are potential markers for malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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