Thermo Fisher Scientific Human CD264 (TRAIL-R4) Synthetic Peptide
인간 DcR2의 세포내 도메인 근처 15개 아미노산 서열을 기반으로 한 합성 펩타이드로, PA5-19896 항체의 블로킹 펩타이드로 사용 가능. TRAIL-R4 관련 연구에 적합하며, 액상 형태로 제공되고 PBS/BSA 버퍼에 보존됨. 연구용 전용 제품.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the intracellular domain of human DcR2.
PEP-0022 can be used as a blocking peptide with polyclonal antibody PA5-19896.
Target Information
TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines.
A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis.
Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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