Thermo Fisher Scientific Human FLIP Synthetic Peptide
Human FLIP 단백질의 C-말단 19개 아미노산 서열에 해당하는 합성 펩타이드로, FLIP 관련 항체의 블로킹 실험에 사용 가능. 액상 형태로 제공되며 PBS 버퍼에 보존. 연구용으로만 사용.
- 카탈로그번호
- PEP0025
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the carboxy terminus of human FLIP.
PEP-0025 can be used as a blocking peptide with polyclonal antibody PA5-19899.
Target Information
FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6-mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC), thereby blocking further recruitment and processing of caspase-8 at the complex. Full-length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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