Thermo Fisher Scientific KLF7 Polyclonal Antibody
Human KLF7 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용하며, 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific KLF7 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KLF7. Recombinant protein control fragment (Product #RP-100752). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643142 |
Product Specific Information
Immunogen sequence:
EAAICEKSSA VDILLSRDKL LSETCLSLQP ASSSLDSYTA VNQAQLNAVT SLTPPSSPEL SRHLVKTSQT LSAVDGTVTL KLVAKKAALS SVKVGGVATA AAAVTAAGAV KSGQSDSDQG G
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 95%
Target Information
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members of this family regulate cell proliferation, differentiation, and survival, and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites.
This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes.
A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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