Thermo Fisher Scientific PRAME Polyclonal Antibody
PRAME 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. Human 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Flow Cytometry (Flow) | 1:25 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 476–502 amino acids from the C-terminal region of human MAPE (PRAME, UniProt ID: P78395-1, NCBI Node ID: 9606, Antigen Range: 476–502, Antigen Length: 509) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2169347 |
Target Information
This gene encodes an antigen predominantly expressed in human melanomas and recognized by cytolytic T lymphocytes. It is not expressed in normal tissues except testis. The expression pattern resembles other cancer/testis (CT) antigens such as MAGE, BAGE, and GAGE. Unlike these, PRAME is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-13679_PRAME_P78395-1_Rabbit.svg, PA5-13679_PRAME_P78395-1_Rabbit_PDP.jpeg)
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