Thermo Fisher Scientific Transferrin Polyclonal Antibody
Transferrin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human 및 Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 261–525 of Human Transferrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.51 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547044 |
Product Specific Information
- Recommended positive controls: HepG2, rat plasma
- Predicted reactivity: Chimpanzee (98%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Transferrins (Tf) are approximately 80 kDa blood plasma glycoproteins synthesized by the liver. They are iron-binding transport proteins capable of binding two Fe³⁺ ions along with an anion, usually bicarbonate. Transferrin is responsible for iron transport from absorption and heme degradation sites to storage and utilization sites. Under normal conditions, about one-third of total blood transferrin carries bound iron. Measurement of transferrin levels serves as an indicator of blood iron-carrying capacity and can reveal abnormalities such as anemia, iron overload, and hemochromatosis. Serum transferrin may also play a role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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