Thermo Fisher Scientific CD85j (ILT2) Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 1:5,000–1:20,000

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, Jurkat, Raji
• Predicted reactivity: Human (98%), Rhesus Monkey (83%), Chimpanzee (89%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, located at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors, containing two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells, binds to MHC class I molecules on antigen-presenting cells, and transduces a negative signal that inhibits stimulation of an immune response. It helps control inflammatory responses and cytotoxicity to focus immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been identified for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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