
Thermo Fisher Scientific PD-L1 (CD274) Polyclonal Antibody
Thermo Fisher Scientific의 PD-L1 (CD274) Polyclonal Antibody는 마우스 및 랫트에서 반응하는 토끼 유래 IgG 항체입니다. Western blot과 ELISA에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 종양 면역 회피 연구 등 PD-L1 관련 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| ELISA | 0.1–0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived mouse PD-L1 recombinant protein (Position: F19–T238) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746090 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. Its receptor, programmed death receptor 1 (PD-1), negatively regulates T-cell receptor (TCR) signaling. Upon binding to PD-1, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant on many murine and human cancers and can be upregulated upon IFN-gamma stimulation, suggesting a key role in tumor immune evasion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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