Thermo Fisher Scientific USP8 Polyclonal Antibody
USP8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 고순도 항원 친화 크로마토그래피로 정제됨. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human USP8 (UniProt ID: P40818-1, Antigen range: 1–1118) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720831 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
USP8 is a ubiquitin-specific protease that plays a regulatory role in protein turnover by preventing degradation. It is involved in cell proliferation and regulates the stability of STAM2 and RASGRF1. USP8 may also regulate T-cell energy mediated by RNF128 through complex formation with RNF128 and STAM2. Structural studies show USP8 forms a ternary complex with RNF128 and OTUB1, interacting with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 increases upon growth stimulation in starved human fibroblasts and decreases upon growth arrest induced by cell-cell contact.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-77104_USP8_P40818-1_Rabbit.svg)
(이미지: PA5-77104_USP8_P40818-1_Rabbit_PDP.jpeg)
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