Thermo Fisher Scientific THNSL2 Polyclonal Antibody
THNSL2 단백질을 인식하는 Goat Polyclonal Antibody로, WB 및 IHC(P) 적용 가능. Human 시료 반응성 확인됨. 액상 형태로 0.5 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-SRFRHREVVHLSR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933636 |
Product Specific Information
- This antibody is expected to recognize isoform 1 (NP_060741.3) and isoform 2 (NP_001231605.1) only.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
THNSL2 (threonine synthase-like 2), also known as TSH2, is a 484 amino acid protein belonging to the threonine synthase family. Utilizing pyridoxal phosphate as a cofactor, THNSL2 may function as a catabolic phospholyase on gamma and beta phosphorylated substrates. THNSL2 may also degrade O-phospho-threonine to alpha-ketobutyrate, ammonia, and phosphate.
Existing as four alternatively spliced isoforms, THNSL2 is encoded by a gene mapping to human chromosome 2p11.2. Chromosome 2 accounts for approximately 8% of the human genome and contains over 1,400 genes. Several genetic disorders are associated with genes on this chromosome, including Harlequin ichthyosis (ABCA12 gene), sitosterolemia (ABCG5/ABCG8 defects), and Alstrom syndrome (ALMS1 gene mutations).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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