Thermo Fisher Scientific Sequestosome-1 Polyclonal Antibody, FITC
Sequestosome-1 단백질을 인식하는 FITC 결합 폴리클로날 항체. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. 친화 크로마토그래피 정제, 형광 검출용 FITC 컨주게이트. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–440 of human Sequestosome-1 protein |
| Conjugate | FITC (Fluorescein isothiocyanate) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in the dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway. The protein functions as a scaffolding/adaptor molecule in concert with TNF receptor-associated factor 6 (TRAF6) to mediate NF-κB activation in response to upstream signals. Alternatively spliced transcript variants encoding the same or different isoforms have been identified. Mutations in this gene are associated with sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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