Thermo Fisher Scientific Sequestosome-1 Polyclonal Antibody
Sequestosome-1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 액상 항체로, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 400–440 of human Sequestosome-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-κB) signaling pathway. It functions as a scaffolding/adaptor protein together with TNF receptor-associated factor 6 to mediate NF-κB activation in response to upstream signals. Alternatively spliced transcript variants encoding the same or different isoforms have been identified. Mutations in this gene are associated with sporadic and familial Paget disease of bone.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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