Thermo Fisher Scientific SOCS5 Polyclonal Antibody
Human SOCS5 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 비결합 상태의 액상 형태입니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 보관하십시오.
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Thermo Fisher Scientific SOCS5 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SOCS5. Recombinant protein control fragment (Product #RP-102073). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789893 |
Product Specific Information
Immunogen sequence:
HLIKQHTAPV SPHSTFFDTF DPSLVSTEDE EDRLRERRRL SIEEGVDPPP NAQIHTFEAT AQVNPLYKLG PKLAPGMTEI SGDSSAIPQA NCDSEEDTTT LCLQSRRQKQ RQISGDSHTH VSRQGAWKVH TQI
Target Information
Cytokine receptor signaling is negatively regulated by the SOCS (Suppressor of Cytokine Signaling) family, which includes SOCS-1 through SOCS-7 and CIS. These proteins contain an N-terminal variable region, a central SH2 domain, and a C-terminal SOCS box motif. SOCS proteins function as part of a classical negative feedback loop regulating cytokine signal transduction via STAT-induced transcriptional mechanisms. Transcription of SOCS genes occurs rapidly in response to cytokines, and each member inhibits signaling through distinct mechanisms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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