Thermo Fisher Scientific CTSL1 Monoclonal Antibody (OTI2H2), TrueMAB

Thermo Fisher Scientific CTSL1 Monoclonal Antibody (OTI2H2), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform additional desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CTSL1 (Cathepsin L) is a lysosomal cysteine proteinase involved in intracellular protein catabolism.
It degrades substrates such as collagen, elastin, and alpha-1 protease inhibitor, regulating neutrophil elastase activity.
The protein is associated with pathological processes including myofibril necrosis, myocardial ischemia, and renal tubular response to proteinuria.
A member of the peptidase C1 family, CTSL1 forms a disulfide-linked dimer of heavy and light chains derived from a single precursor.
Multiple transcript variants encoding the same protein have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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