Thermo Fisher Scientific CTSL1 Monoclonal Antibody (OTI2H2), TrueMAB
CTSL1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 IHC(P)에서 검증됨. Human에 반응하며, 무보존제 PBS 버퍼에 동결건조 형태로 제공. 단백질 분해 및 세포 내 단백질 대사 연구에 적합.
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Thermo Fisher Scientific CTSL1 Monoclonal Antibody (OTI2H2), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H2 |
| Immunogen | Full length human recombinant protein of human CTSL1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform additional desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CTSL1 (Cathepsin L) is a lysosomal cysteine proteinase involved in intracellular protein catabolism.
It degrades substrates such as collagen, elastin, and alpha-1 protease inhibitor, regulating neutrophil elastase activity.
The protein is associated with pathological processes including myofibril necrosis, myocardial ischemia, and renal tubular response to proteinuria.
A member of the peptidase C1 family, CTSL1 forms a disulfide-linked dimer of heavy and light chains derived from a single precursor.
Multiple transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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