Thermo Fisher Scientific PLSCR1 Monoclonal Antibody (1E9)
PLSCR1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot 등 연구용 분석에 적합합니다. 칼슘 의존적 인지질 스크램블레이스 기능 연구에 활용됩니다. 액상 형태로 -20°C 보관하며, 드라이아이스로 배송됩니다.
- 카탈로그번호
- 44318M
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PLSCR1 Monoclonal Antibody (1E9)
Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E9 |
| Immunogen | Peptide conjugated to hemocyanin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Dry ice |
| RRID | AB_2533630 |
Target Information
The calcium-dependent plasma membrane protein phospholipid scramblase 1 (PLSCR1) contributes to the transbilayer movement of phosphatidylserine and other membrane phospholipids upon influx of calcium into the cytosol. This movement results in plasma membrane phospholipid remodeling and surface exposure of phosphatidylserine in injured or apoptotic cells, leading to cell death.
Interferons and other cytokines induce expression of PLSCR1, implying that PLSCR1 also functions in cytokine signaling pathways.
EGF stimulation results in tyrosine phosphorylation of PLSCR1 on tyrosines 69 and 74, allowing it to interact with Shc, thereby connecting Src kinase activation to stimulation of the EGF receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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