Thermo Fisher Scientific Cytokeratin 16 (KRT16) (Suprabasal Keratinocyte Marker) Monoclonal Antibody (SPM264)
인간 KRT16 단백질을 인식하는 단일클론 항체로, 상피세포 구조 연구에 적합합니다. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 고순도 Protein A/G 정제, 액상 형태로 제공되며 안정적 보관 용이.
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Thermo Fisher Scientific Cytokeratin 16 (KRT16) Monoclonal Antibody (SPM264)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM264 |
| Immunogen | Recombinant fragment from the C-terminal of human Cytokeratin 16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins arranged in heterotypic pairs and are clustered in chromosome region 17q12–q21.
This keratin is coexpressed with keratin 14 in epithelial tissues such as esophagus, tongue, and hair follicles. Mutations in KRT16 are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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