Thermo Fisher Scientific FMR1 Monoclonal Antibody (OTI1D10), TrueMAB
FMR1 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, WB, IHC, Flow Cytometry 등에 사용 가능. 인간, 마우스, 랫, 개 등 다양한 종에 반응. 고순도 액상 형태로 -20°C에서 안정 저장. 연구용으로만 사용.
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Thermo Fisher Scientific FMR1 Monoclonal Antibody (OTI1D10), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 36–279 of human FMR1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5′ UTR is normally found at 6–53 copies, but an expansion to 55–230 repeats causes fragile X syndrome. Expansion of this repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants encoding different protein isoforms located in distinct cellular compartments have been described for this gene.
Additional Information
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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