Thermo Fisher Scientific NPHP3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NPHP3. Recombinant protein control fragment (Product #RP-89775). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NPHP3,uniProtId:Q7Z494-1,ncbiNodeId:9606,antigenRange:256-360,antigenLength:1330,antigenImageFileName:PA5-52656_NPHP3_Q7Z494-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52656_NPHP3_Q7Z494-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644767

Product Specific Information

Immunogen sequence: PEFAHSSIDV EGPFANVNRD DWDIAVASLL QVTPLFSHSL WSNTVRCYLI YTDETQPEMD LFLKDYSPKL KRMCETMGYF FHAVYFPIDV ENQYLTVRKW EIEKS

Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

Target Information

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.