Thermo Fisher Scientific NPHP3 Polyclonal Antibody
Human NPHP3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% glycerol) 내 액상 형태. 세포 섬모 발달 및 Wnt 신호 조절 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NPHP3. Recombinant protein control fragment (Product #RP-89775) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644767 |
Product Specific Information
Immunogen sequence:
PEFAHSSIDV EGPFANVNRD DWDIAVASLL QVTPLFSHSL WSNTVRCYLI YTDETQPEMD LFLKDYSPKL KRMCETMGYF FHAVYFPIDV ENQYLTVRKW EIEKS
Sequence identity to orthologs:
- Mouse: 90%
- Rat: 89%
Target Information
Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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