Thermo Fisher Scientific PDE3B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PDE3B. Recombinant protein control fragment (Product #RP-106687). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE3B,uniProtId:Q13370-1,ncbiNodeId:9606,antigenRange:513-658,antigenLength:1112,antigenImageFileName:PA5-84277_PDE3B_Q13370-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84277_PDE3B_Q13370-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791429

Product Specific Information

Immunogen sequence: LSPVNSSNHG PVSTGSLTNR SPIEFPDTAD FLNKPSVILQ RSLGNAPNTP DFYQQLRNSD SNLCNSCGHQ MLKYVSTSES DGTDCCSGKS GEEENIFSKE SFKLMETQQE EETEKKDSRK LFQEGDKWLT EEAQSEQQTN IEQEVS

Target Information

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.