Thermo Fisher Scientific NIM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NIM1. Recombinant protein control fragment (Product #RP-89814). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NIM1,uniProtId:Q8IY84-1,ncbiNodeId:9606,antigenRange:22-143,antigenLength:436,antigenImageFileName:PA5-52467_NIM1_Q8IY84-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52467_NIM1_Q8IY84-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644679

Product Specific Information

Immunogen sequence: RDSVESGCQT ESSKEGEEGQ PRQLTPFEKL TQDMSQDEKV VREITLGKRI GFYRIRGEIG SGNFSQVKLG IHSLTKEKVA IKILDKTKLD QKTQRLLSRE ISSMEKLHHP NIIRLYEVVE TL

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Target Information

NIM1K serine/threonine kinase or NIM1 belongs to CAMK kinase family. Unlike to other AMPK-related kinases, NIM1 cannot be phosphorylated and activated by LKB1. Two somatic mutations (P333S and P411T) were found in lung neuroendocrine carcinoma and lung large cell carcinoma samples. NIM1 gene ontology (GO) annotations include cellular response to glucose starvation; intracellular signal transduction; negative regulation of TOR signaling; protein phosphorylation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.