Thermo Fisher Scientific Axiom Asia Precision Medicine Research Array Kit, 24-format

Applied Biosystems™ Axiom™ Asia Precision Medicine Research Array Kit, 24-format

The Axiom Asia Precision Medicine Research Array (PMRA) is a comprehensive imputation-aware genotyping array with more than 750,000 markers.
High-value content on the array is associated with both common and rare diseases for clinical research and disease association studies in East and South Asian populations.

This array kit includes:

• 4x24-format array plate
• Axiom 2.0 Reagent Kit
• Four Axiom GeneTitan Consumables kits

주요 특징

• Genome-wide association studies (GWAS) imputation module with >540,000 markers from South and East Asian populations
• Broad coverage of common and rare variants associated with human health
• Minimum order size: one kit (one 96-array plate, Axiom reagents, GeneTitan MC consumables for 96 samples)
• Customizable with up to 50,000 markers without affecting imputation accuracy, or fully customizable as required

적용 분야

• 정밀의학 연구 및 장기 코호트 연구
• 바이오뱅킹 및 전임상·임상 연구
• Direct-to-consumer 유전체 분석
• 약물 발견 및 임상시험

커버리지

• GWAS variants
• Evidence-based markers of clinical relevance (pharmacogenomics, ClinVar, ACMG, exclusive markers)
• Immune-related markers (HLA, KIR, autoimmune and inflammatory)
• Functional variants (loss of function, eQTL, nonsynonymous variants, lung phenotypes)
• Disease-related variants (Alzheimer’s, cardiometabolic, neurological, diabetes, cancer, cardiac, rare variants)
• Tracking-related variants (fingerprint, sample tracking, mitochondrial, Y chromosome)

사양