Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI3G10), TrueMAB
Human ESRRA 단백질(aa 206-417)을 항원으로 제작된 Mouse Monoclonal Antibody. Western Blot에 최적화되어 있으며, Lyophilized 형태로 제공. PBS buffer(8% trehalose) 기반, 보존제 무첨가. -20°C 보관, 연구용 전용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 206–417 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882) prior to use.
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily.
ERR family members share a highly conserved DNA-binding domain with 68% amino acid identity to the estrogen receptor.
ERR1 binds to the ERR-alpha response element (ERRE, 5’-tnaaggtca-3’) and regulates the medium-chain acyl-CoA dehydrogenase (MCAD) promoter.
It functions as a metabolic regulator, predominantly expressed in tissues that metabolize fatty acids.
The corresponding gene for ERR1 is NR3B1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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