Thermo Fisher Scientific ESRRA Monoclonal Antibody (OTI1C6), TrueMAB
인간 ESRRA 단백질(아미노산 206-417)에 특이적인 단클론 항체입니다. Western blot에 최적화되어 있으며, 무보존제 동결건조 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 대사 조절 관련 연구에 적합합니다.
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Applications
Tested Application
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 206–417 of human ESRRA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily.
ERR family members share a highly conserved DNA-binding domain (68% amino acid identity with the estrogen receptor).
ERRα binds to the ERRα response element (ERRE) and may regulate the medium-chain acyl-CoA dehydrogenase (MCAD) promoter.
It functions as a metabolic regulator and is highly expressed in tissues that preferentially metabolize fatty acids.
The corresponding gene for ERR1 is NR3B1.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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