Thermo Fisher Scientific Human NOD1 Synthetic Peptide
인간 NOD1 단백질의 C-말단 16개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-21015의 블로킹 펩타이드로 사용 가능. 면역 반응 연구 및 NOD1 기능 분석에 적합. 액상 형태, 200 µg/mL, -20°C 보관.
- 카탈로그번호
- PEP1129
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human NOD1.
PEP-1129 can be used as a blocking peptide with polyclonal antibody PA5-21015.
Target Information
NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins involved in innate immune defense.
NOD1 contains:
- An N-terminal caspase recruitment domain (CARD)
- A centrally located nucleotide-binding domain (NBD)
- Ten tandem leucine-rich repeats (LRRs) in its C-terminus
The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-kappa-B.
LRRs participate in protein-protein interactions, and mutations in the NBD may affect oligomerization and subsequent LRR domain function.
This protein acts as an intracellular pattern-recognition receptor (PRR) initiating inflammation in response to certain bacteria via detection of bacterial diaminopimelic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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