Thermo Fisher Scientific Caspase 1 p20 Polyclonal Antibody
Caspase-1 p20 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Mouse 및 Rat에서 반응하며 Western blot에 적합. Lyophilized 형태로 제공되며, 높은 특이성과 재현성을 갖춘 연구용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of mouse CASP1 (137–157aa LEKAQKLWKENPSEIYPIMNT) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746031 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Caspase-1 (CASP1) is a thiol protease that cleaves IL-1 beta between Asp and Ala, leading to the release of mature cytokine involved in inflammatory processes. CASP1 plays a key role in pathogen defense, activates sterol regulatory element binding proteins (SREBPs), and promotes apoptosis. Upon inflammasome activation during DNA virus infection, CASP1 controls antiviral immunity through cleavage of CGAS, rendering it inactive.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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