Thermo Fisher Scientific CD62L Monoclonal Antibody (IVA94)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent

Flow Cytometry (Flow)

• Tested Dilution: 1–4 µg/mL

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Product Specifications

Additional Formats

• Alexa Fluor 488
• Request custom conjugation

Product Specific Information

This antibody reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74–95 kDa single-chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes, and granulocytes. It is also present on a subset of NK cells and certain hematopoietic malignant cells.

Target Information

Human CD62L is a 74–95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin is composed of:

• An aminoterminal C-type lectin binding domain
• An epidermal growth factor-like domain
• Two short consensus repeat (SCR) sequences homologous to complement binding proteins
• A short spacer region
• A transmembrane region
• A short cytoplasmic region

Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes, and polymorphonuclear cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.