Thermo Fisher Scientific CD9 Monoclonal Antibody (IVA50)
CD9 단백질을 인식하는 Mouse IgG2 단일클론 항체로 인간 및 소 반응성. Western blot, ICC/IF, Flow cytometry 등 다양한 응용 가능. 액상 형태, Protein A 정제, 4°C 보관. 세포 활성 및 분화 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 3 publications |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | Assay-dependent | View publications |
| Immunoprecipitation (IP) | Assay-dependent | View 1 publication |
| Neutralization (Neu) | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Bovine, Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IVA50 |
| Immunogen | Bovine thrombocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073475 |
Product Specific Information
This antibody reacts with CD9 on human platelets.
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, neurons, and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family, which spans the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation, possibly through association with integrin CD41/CD61 (GPIIb/GPIIIa).
CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. It plays roles in cell attachment, proliferation, and is necessary for association of heterologous MHC II molecules on dendritic cells, which is important for effective T cell stimulation.
Expression of CD9 is critical for suppression of cancer cell motility and metastasis and is considered a metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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