Thermo Fisher Scientific APC4 Polyclonal Antibody
APC4 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 인간 시료에 반응. 항원 친화 크로마토그래피로 정제, 4°C 보관.
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Thermo Fisher Scientific APC4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 425 and 475 of human anaphase-promoting complex subunit 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse and Orangutan
Target Information
The anaphase-promoting complex (APC), also known as the cyclosome, promotes metaphase-anaphase transition by ubiquitinating substrates such as mitotic cyclins and anaphase inhibitors, which are then degraded by the 26S proteasome. The vertebrate APC contains eight subunits, and its composition is highly conserved from yeast to humans. Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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