Thermo Fisher Scientific RING1 Recombinant Rabbit Monoclonal Antibody (ARC2278)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC2278

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RING1A A (Q06587) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RING1,uniProtId:Q06587-1,ncbiNodeId:9606,antigenRange:100-200,antigenLength:406,antigenImageFileName:MA5-37980_RING1_Q06587-1_Rabbit.svg,antigenImageFileNamePDP:MA5-37980_RING1_Q06587-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897898

Product Specific Information

Positive Samples: HeLa, HCT116

Immunogen sequence: DPNFDALISK IYPSREEYEA HQDRVLIRLS RLHNQQALSS SIEEGLRMQA MHRAQRVRRP IPGSDQTTTM SGGEGEPGEG EGDGEDVSSD SAPDSAPGPA P

Target Information

This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.