Thermo Fisher Scientific H-cadherin Monoclonal Antibody (392411)
H-cadherin 단백질을 인식하는 Rat IgG2a 단일클론 항체로, Western blot, IHC(F), Flow Cytometry에 적합합니다. 인간 Cadherin-13에 특이적이며 다른 Cadherin과 교차반응이 없습니다. 연구용으로만 사용되며 -20°C에서 보관합니다.
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Thermo Fisher Scientific H-cadherin Monoclonal Antibody (Clone 392411)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 8–25 µg/mL |
| Flow Cytometry (Flow) | 0.25 µg per million cells |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 392411 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Cadherin-13 (Glu23–Ala692) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608494 |
Product Specific Information
- In direct ELISAs and Western blots, no cross-reactivity with recombinant human E-Cadherin, N-Cadherin, P-Cadherin, VE-Cadherin, Cadherin-8, -11, -12, or -17 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3′ trailer from precursor tRNAs. It interacts with activated Smad2 and its nuclear partner forkhead box H1 (FAST-1). Reduced expression can suppress TGF-β–induced growth arrest, and mutations in this gene are associated with increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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