Thermo Fisher Scientific Atypical Chemokine Receptor D6 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal Antibody로, Western Blot, ELISA, Immunoprecipitation에 사용 가능. 합성 펩타이드(AA 200–300) 기반 면역원으로 제작. 액상 형태, 친화 크로마토그래피로 정제, -20°C 보관.
- 카탈로그번호
- ACRD6-601AP
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 200–300 on ACRD6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a beta chemokine receptor predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to inflammation sites.
This gene is expressed in a range of tissues and hemopoietic cells. Expression in lymphatic endothelial cells and overexpression in vascular tumors suggest its role in chemokine-driven leukocyte recirculation and vascular tumor development.
The receptor binds most beta-chemokine family members, though its specific function remains unknown.
This gene is mapped to chromosome 3p21.3, a region containing a cluster of chemokine receptor genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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