Thermo Fisher Scientific Urocortin Polyclonal Antibody
Urocortin 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, PBS/glycerol buffer에 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human UCN (Accession P55089), corresponding to amino acid residues L19–G69. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853772 |
Product Specific Information
Antibody detects endogenous levels of total Urocortin.
Target Information
Urocortin (UCN) is a 40-amino-acid neuropeptide widely distributed in the central nervous system (CNS). It belongs to a family of structurally related peptides including corticotrophin releasing factor (CRF), sauvagine, and urotensin I. Urocortin is derived from a larger precursor protein (pro-urocortin, also known as corticotensin). It exhibits biological actions similar to CRF, such as stress-related endocrine, autonomic, and behavioral responses in mammals. Urocortin is a potent stimulator of adrenocorticotropic hormone (ACTH) secretion by corticotroph cells from the anterior pituitary in vitro and in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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