Thermo Fisher Scientific Mouse BST-2 Synthetic Peptide
마우스 BST-2 단백질의 N-말단 부위 18개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20538과 함께 블로킹 펩타이드로 사용 가능. PBS(pH 7.2) 내 0.1% BSA 포함, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP0658
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of mouse Bst2.
PEP-0658 can be used as a blocking peptide with polyclonal antibody PA5-20538.
Target Information
BST2 (CD317, HM1.24 antigen, DAMP-2, tetherin) is an integral membrane protein involved in the development and growth of B-cells. The surface expression of BST2 on fibroblast cell lines facilitates the stromal cell-dependent growth of DW34, a pre-B-cell line.
BST2 is highly expressed during B-cell development, from pro-B precursors to plasma cells, T-cells, monocytes, NK cells, DCs, and myeloma cells.
Studies show BST2 functions as an inhibitor of retrovirus release from human cells, counteracted by the HIV-1 accessory protein Vpu. BST2-mediated virion retention or endocytosis can be abolished by depletion, suggesting a potential therapeutic target for HIV/AIDS.
BST2 dysfunction is also associated with stomatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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