Thermo Fisher Scientific PIM1 Polyclonal Antibody
Thermo Fisher Scientific의 PIM1 Polyclonal Antibody는 Rat 시료에 반응하며 Western blot 및 ELISA에 적합합니다. 재조합 인간 PIM1 단백질(aa 1–313)을 면역원으로 사용한 Rabbit IgG 항체로, 액상 형태이며 1.9 mg/mL 농도로 제공됩니다. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–313 of human PIM1 (NP_002639.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.90 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804096 |
Product Specific Information
Immunogen sequence:
MLLSKINSLA HLRAAPCNDL HATKLAPGKE KEPLESQYQV GPLLGSGGFG SVYSGIRVSD NLPVAIKHVE KDRISDWGEL PNGTRVPMEV VLLKKVSSGF SGVIRLLDWF ERPDSFVLIL ERPEPVQDLF DFITERGALQ EELARSFFWQ VLEAVRHCHN CGVLHRDIKD ENILIDLNRG ELKLIDFGSG ALLKDTVYTD FDGTRVYSPP EWIRYHRYHG RSAAVWSLGI LLYDMVCGDI PFEHDEEIIR GQVFFRQRVS SECQHLIRWC LALRPSDRPT FEEIQNHPWM QDVLLPQETA EIHLHSLSPG PSK
Positive Samples: Rat kidney
Cellular Location: Cell membrane, Cytoplasm, Nucleus
Target Information
The proto-oncogene PIM1 is upregulated in prostate cancer. PIM1, a member of the Serine/Threonine protein kinase family, is involved in signal transduction in blood cells. It may regulate chromatin structure or silencing by phosphorylating HP1 gamma/CBX3. PIM1 is primarily expressed in hematopoietic and germ line cells.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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