Thermo Fisher Scientific Phospho-ETK (Tyr40) Polyclonal Antibody
Phospho-ETK (Tyr40) 폴리클로날 항체로, 인산화된 BMX 단백질의 Tyr40 잔기를 특이적으로 검출. 인간 및 마우스 시료에 반응하며 Western blot에 최적화. 고순도 정제, 액상 형태로 안정적 보관 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BMX (Accession P51813), corresponding to amino acid residues around phosphorylated Tyr40 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816658 |
Product Specific Information
Antibody detects endogenous levels of BMX only when phosphorylated at Tyr40.
Target Information
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase belonging to the SRC-related TEC subfamily. It regulates various cellular processes such as apoptosis, cell survival, differentiation, migration, and transformation. Related genes include TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300), all homologs of the Drosophila Src28 TK and containing SH3 and SH2 domains upstream of the TK domain.
[Supplied by OMIM]
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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