Thermo Fisher Scientific PLD1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PLD1 for WB and ELISA applications. Recognizes cytoplasmic and membrane-associated PLD1. Supplied as liquid, unconjugated, affinity-purified with 1.57 mg/mL concentration. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 875–1036 of human PLD1 (NP_0011235531) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.57 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805961 |
Product Specific Information
- Immunogen sequence:
NINDRSMLGK RDSEMAVIVQ DTETVPSVMD GKEYQAGRFA RGLRLQCFRV VLGYLDDPSE DIQDPVSDKF FKEVWVSTAA RNATIYDKVF RCLPNDEVHN LIQLRDFINK PVLAKEDPIR AEEELKKIRG FLVQFPFYFL SEESLLPSVG TKEAIVPMEV WT - Positive Samples: HeLa, HT-29, LO2
- Cellular Location: Cytoplasm, cytoplasmic side, endoplasmic reticulum membrane, Golgi apparatus membrane, late endosome membrane, lipid-anchor, perinuclear region
Target Information
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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