Thermo Fisher Scientific PLD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 875-1036 of human PLD1 (NP_0011235531) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PLD1,uniProtId:Q13393-1,ncbiNodeId:9606,antigenRange:875-1036,antigenLength:1074,antigenImageFileName:PA5-90209_PLD1_Q13393-1_Rabbit.svg,antigenImageFileNamePDP:PA5-90209_PLD1_Q13393-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.57 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805961

Product Specific Information

Immunogen sequence: NINDRSMLGK RDSEMAVIVQ DTETVPSVMD GKEYQAGRFA RGLRLQCFRV VLGYLDDPSE DIQDPVSDKF FKEVWVSTAA RNATIYDKVF RCLPNDEVHN LIQLRDFINK PVLAKEDPIR AEEELKKIRG FLVQFPFYFL SEESLLPSVG TKEAIVPMEV WT; Positive Samples: HeLa, HT-29, LO2; Cellular Location: Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Golgi apparatus membrane, Late endosome membrane, Lipid-anchor, perinuclear region

Target Information

Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.