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Thermo Fisher Scientific IL-1 beta Polyclonal Antibody
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Thermo Fisher Scientific IL-1 beta Polyclonal Antibody

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인간 IL-1 beta를 인식하는 염소 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 액상 형태로 제공되며, 0.5 mg/mL 농도로 TBS(pH 7.3)와 0.5% BSA, 0.02% sodium azide를 포함합니다. -20°C에서 보관하며 동결-해동을 피해야 합니다.

카탈로그번호
PA5143127
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오전 02:39
Thermo Fisher Scientific PA5143127 IL-1 beta Polyclonal Antibody 100 ug pk판매 단위 pk ·
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681,400원VAT 포함 749,540원

Thermo Fisher Scientific · Thermo Fisher Scientific IL-1 beta Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1–3 µg/mL

Publications


Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Goat / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide with sequence C-QLESVDPKNYPKK (aa 197–209)
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Ammonium sulfate precipitation
Storage Buffer TBS, pH 7.3, with 0.5% BSA
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Wet ice
RRID AB_2933766

Product Specific Information

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.


Target Information

Interleukin-1 beta (IL-1β) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. It is synthesized as a 31 kDa inactive pro-form that accumulates in the cytosol and requires inflammasome activation for cleavage into the active 17 kDa protein. IL-1β signals through IL-1RI and IL-1RII receptors, sharing these with IL-1α. Its activity is regulated by IL-1 Receptor Antagonist (IL-1RA), which competitively inhibits receptor binding. IL-1β plays a key role in innate immune defense and inflammation, and elevated levels are associated with chronic inflammatory conditions.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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