ELK Biotechnology SMRTe rabbit pAb
SMRTe(NCOR2) 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, WB, ELISA에 사용 가능. 핵 내 발현 단백질 검출에 적합하며, 인간, 랫드, 마우스 시료에 반응. -20°C 보관 시 1년 안정.
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제품명
SMRTe rabbit pAb
제품 개요
SMRTe(NCOR2) 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. 이 항체는 핵 수용체 코리프레서로 작용하는 단백질을 검출하며, 다양한 응용 분야(IHC, IF, WB, ELISA)에 사용 가능합니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Product name | SMRTe rabbit pAb |
| Alternative Names | NCOR2; CTG26; Nuclear receptor corepressor 2; N-CoR2; CTG repeat protein 26; SMAP270; Silencing mediator of retinoic acid and thyroid hormone receptor; SMRT; T3 receptor-associating factor; TRAC; Thyroid-; retinoic-acid-receptor-associated |
| Applications | IHC; IF; WB; ELISA |
| Recommended Dilutions | WB: 1:500–1:2000 Immunohistochemistry: 1:100–1:300 Immunofluorescence: 1:200–1:1000 ELISA: 1:20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human NCOR2 (AA range: 511–560) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 270 kDa |
| Gene ID (Human) | 9612 |
| Human Swiss-Prot No. | Q9Y618 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
(provided by RefSeq, Apr 2011)
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