
ELK Biotechnology GABAB R2 rabbit pAb
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Product name: | GABAB R2 rabbit pAb |
Alternative Names: | GABBR2; GPR51; GPRC3B; Gamma-aminobutyric acid type B receptor subunit 2; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; HG20 |
Applications: | WB;ELISA |
Recommended Dilutions: | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: | Synthesized peptide derived from GABAB R2 . at AA range: 830-910 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 105kD |
GeneID(Human): | 9568 |
Human Swiss-Prot No: | O75899 |
Cellular localization: | Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane. . |
Background: | The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010], |
Species Reactivity: | Human;Mouse;Rat |
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