ELK Biotechnology ALDH1A2 rabbit pAb
ALDH1A2 rabbit polyclonal antibody는 인간, 마우스, 랫트 시료에서 반응하며 WB, IHC, IF, ELISA에 사용 가능. Retinoic acid 합성 관련 효소를 인식하며, 고순도 IgG 형태로 안정적 보관 가능. -20°C에서 1년간 보관.
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제품명
ALDH1A2 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ALDH1A2; RALDH2; Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II) |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 IHC-p: 1/50 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ALDH1A2 (AA range: 412–461) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 52 kD |
| GeneID (Human) | 8854 |
| Human Swiss-Prot No | O94788 |
| Cellular Localization | Cytoplasm |
| Storage | -20°C / 1 year |
| Host Species | Rabbit |
Background
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. Studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1 concurrently establish local embryonic retinoic acid levels, facilitating posterior organ development and preventing spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
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