Thermo Fisher Scientific Phospho-Caveolin 2 (Ser23) Polyclonal Antibody
Phospho-Caveolin 2 (Ser23)를 인식하는 Rabbit Polyclonal 항체로, 인산화된 Caveolin 2의 내인성 발현을 검출. WB 및 IHC(P) 실험에 적합하며, Human, Mouse, Rat 등 다양한 종에 반응. 1 mg/mL 농도의 액상 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAV2 (Accession P51636), corresponding to amino acid residues around phosphorylated Ser23. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903135 |
Product Specific Information
Antibody detects endogenous levels of Caveolin 2 only when phosphorylated at Ser23.
Target Information
Caveolae are specialized domains of the plasma membrane involved in the sequestration of lipid and protein molecules. These structures play key roles in lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins.
There are three members of the caveolin multigene family encoding 21–24 kDa integral membrane proteins that form the major structural component of caveolar membranes. Caveolin-2 is abundantly expressed in fibroblasts, differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. Caveolin-1 shows similar expression patterns, while Caveolin-3 expression is restricted to muscle tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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