Thermo Fisher Scientific Human Bim Synthetic Peptide
인간 Bim 단백질의 중심부 19개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 차단 실험에 사용 가능. 순도 높은 액상 형태로 제공되며 PBS 버퍼에 보존. 연구용으로 인간 Bim 관련 세포사멸 연구에 적합.
- 카탈로그번호
- PEP0027
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Bim Synthetic Peptide
Thermo Fisher Scientific Human Bim Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the center of human Bim.
PEP-0027 can be used as a blocking peptide with polyclonal antibody PA5-19901.
Target Information
BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in diverse cellular activities.
The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It interacts with other BCL-2 family members, including BCL2, BCL2L1/BCL-X(L), and MCL1, functioning as an apoptotic activator.
Expression of this gene can be induced by nerve growth factor (NGF) and the forkhead transcription factor FKHR-L1, suggesting its role in neuronal and lymphocyte apoptosis.
Transgenic mouse studies indicate that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.