Thermo Fisher Scientific Connexin 30 Monoclonal Antibody (CL4540)

Applications

Western Blot (WB)

• Tested Dilution: 정보 없음
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Immunohistochemistry (IHC)

• Tested Dilution: 정보 없음
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Immunocytochemistry (ICC/IF)

• Tested Dilution: 2–10 µg/mL
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Product Specifications

Product Specific Information

Immunogen sequence: RSKRAQTQKN HPNHALKESK

Target Information

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel.
Connexin protein names were previously based on molecular weight, but now use sequential numbers based on gap junction forms. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in families with hidrotic ectodermal dysplasia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.