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Thermo Fisher Scientific NFATC2IP Polyclonal Antibody
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NFATC2IP 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간 시료 반응성. 액상 형태로 제공되며, 친화 크로마토그래피로 정제됨. NFATc2IP 발현 연구 및 Th2 세포 사이토카인 조절 기전 분석에 적합.
- 카탈로그번호
- PA599664
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 02:25
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Thermo Fisher Scientific PA599664 NFATC2IP Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
764,500원VAT 포함 840,950원
Thermo Fisher Scientific · Thermo Fisher Scientific NFATC2IP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NFATC2IP (Accession Q8NCF5), corresponding to amino acid residues A155–P205 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818597 |
Product Specific Information
Antibody detects endogenous levels of total NFATc2IP.
Target Information
In T-helper 2 (Th2) cells, NFATC2IP regulates the magnitude of NFAT-driven transcription of specific cytokine genes, including IL3, IL4, IL5, and IL13, but not IL2. It recruits PRMT1 to the IL4 promoter, enhancing histone H4 Arg-3 methylation and facilitating subsequent histone acetylation at the IL4 locus, thereby promoting robust cytokine expression. It also down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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